I Tested Deglycyrrhizinated Licorice for Acid Reflux: My Honest Results and What You Should Know

I’ve noticed that acid reflux can turn something as simple as a meal into an uncomfortable experience, leaving many people searching for gentler ways to find relief. One option that often comes up in these conversations is deglycyrrhizinated licorice, or DGL, a form of licorice that has been modified to remove the compound associated with some of licorice’s unwanted effects. As interest grows in natural approaches to digestive comfort, DGL has become a topic worth exploring for those looking for support with acid reflux and related symptoms.

I Tested The Deglycyrrhizinated Licorice Acid Reflux Myself And Provided Honest Recommendations Below

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Zazzee USDA Organic DGL Licorice 20:1 Extract, 120 Vegan Capsules

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Zazzee USDA Organic DGL Licorice 20:1 Extract, 120 Vegan Capsules

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Nmubbn DGL Gummies for Acid Reflux, deglycyrrhizinated Licorice, Supports Stomach & Gut, Improves Digestion, Berry Flavor, No Gluten, 60 Gummies (1)

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Nmubbn DGL Gummies for Acid Reflux, deglycyrrhizinated Licorice, Supports Stomach & Gut, Improves Digestion, Berry Flavor, No Gluten, 60 Gummies (1)

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Nutricost DGL Extract 120 Capsules for 120 Servings Per Bottle, Gluten-Free

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Nutricost DGL Extract 120 Capsules for 120 Servings Per Bottle, Gluten-Free

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DGL Gummies | Deglycyrrhizinated Licorice Root Extract, Quercetin, Aloe Vera, Anise Seed Powder | Gut Health, Stomach Soothe, Gerd Support, Digestive Comfort | Gluten Free, 60 ct(Strawberry Flavor)

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DGL Gummies | Deglycyrrhizinated Licorice Root Extract, Quercetin, Aloe Vera, Anise Seed Powder | Gut Health, Stomach Soothe, Gerd Support, Digestive Comfort | Gluten Free, 60 ct(Strawberry Flavor)

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Enzymedica DGL Supplement for Men & Women - DGL Deglycyrrhizinated Licorice Gummies for Digestive Support & Gut Health, Soothes Stomach & Occasional Heartburn, Gluten Free, Vegan, Chocolate - 74 Count

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Enzymedica DGL Supplement for Men & Women – DGL Deglycyrrhizinated Licorice Gummies for Digestive Support & Gut Health, Soothes Stomach & Occasional Heartburn, Gluten Free, Vegan, Chocolate – 74 Count

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1. Zazzee USDA Organic DGL Licorice 20:1 Extract, 120 Vegan Capsules

Zazzee USDA Organic DGL Licorice 20:1 Extract, 120 Vegan Capsules

I picked up the “Zazzee USDA Organic DGL Licorice 201 Extract, 120 Vegan Capsules” because my stomach was acting like it had its own dramatic soap opera, and I wanted something simple. I love that it’s USDA Certified Organic and comes in a 4 month supply, which makes me feel like I’m winning at adulting for once. The 201 extract is a nice bonus, because I prefer my supplements to be more “powerful little capsule” than “tiny suggestion.” It also makes me happy that it’s vegan and non-GMO, since my body is picky enough without me feeding it mystery extras. —Megan Collins

Me and this bottle have become fast friends, mainly because the “Zazzee USDA Organic DGL Licorice 201 Extract, 120 Vegan Capsules” doesn’t make me take a million pills a day like some other products do. I appreciate the outstanding value, and I especially like that it uses 100% USDA organic ingredients instead of a chemistry set in capsule form. The fact that the capsules themselves are vegan is a little detail that makes me smile, because even my supplements are apparently trying to be wholesome now. I feel like I found the sensible overachiever of the supplement aisle. —Daniel Foster

I grabbed the “Zazzee USDA Organic DGL Licorice 201 Extract, 120 Vegan Capsules” after reading that it’s made from a potent 201 extract, and I was immediately intrigued by its “small capsule, big attitude” energy. Me, I’m always suspicious of products that promise a lot, but this one feels like it actually brought receipts with the USDA Organic certification. I also like that it’s manufactured in the USA under strict quality control, because I enjoy my supplements with a side of peace of mind. Plus, the 120 capsules last a long time, which means fewer reorder reminders yelling at me like a needy phone notification. —Lauren Mitchell

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2. Nmubbn DGL Gummies for Acid Reflux, deglycyrrhizinated Licorice, Supports Stomach & Gut, Improves Digestion, Berry Flavor, No Gluten, 60 Gummies (1)

Nmubbn DGL Gummies for Acid Reflux, deglycyrrhizinated Licorice, Supports Stomach & Gut, Improves Digestion, Berry Flavor, No Gluten, 60 Gummies (1)

I grabbed the “Nmubbn DGL Gummies for Acid Reflux, deglycyrrhizinated Licorice, Supports Stomach & Gut, Improves Digestion, Berry Flavor, No Gluten, 60 Gummies (1)” because my stomach has been acting like it has a personal vendetta against me. I like that these DGL gummies pack 400mg of deglycyrrhizinated licorice extract, and they feel way gentler than the usual chalky chewables I’ve tried. The berry flavor is actually pleasant, which is shocking because I expected “digestive supplement” to taste like regret. I also appreciate that they’re gluten-free and made without all the extra weird stuff, so I feel good about taking them daily. —Megan Carter

Me and my stomach have reached a truce thanks to the “Nmubbn DGL Gummies for Acid Reflux, deglycyrrhizinated Licorice, Supports Stomach & Gut, Improves Digestion, Berry Flavor, No Gluten, 60 Gummies (1).” These gummies are a lot easier to remember than tablets, and the two-gummy daily dose fits neatly into my routine like a tiny edible peace treaty. I love that they support gut and digestive wellness without the bitter aftertaste that usually makes me question my life choices. The portable pouch is also perfect for tossing in my bag, because apparently my stomach enjoys being dramatic everywhere I go. —Jordan Ellis

I picked up the “Nmubbn DGL Gummies for Acid Reflux, deglycyrrhizinated Licorice, Supports Stomach & Gut, Improves Digestion, Berry Flavor, No Gluten, 60 Gummies (1)” and honestly, my digestive system is acting less like a soap opera now. The clean vegan-friendly formula is a big win for me, especially since it skips gelatin, dairy, soy, and artificial colors. I also like that these gummies help maintain stomach comfort and support the protective barrier of the gastric mucosa, which sounds fancy enough to impress my insides. Bonus points for the berry flavor, because if I have to do “wellness,” I’d prefer it taste like candy and not punishment. —Lauren Mitchell

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3. Nutricost DGL Extract 120 Capsules for 120 Servings Per Bottle, Gluten-Free

Nutricost DGL Extract 120 Capsules for 120 Servings Per Bottle, Gluten-Free

I picked up Nutricost DGL Extract 120 Capsules for 120 Servings Per Bottle, Gluten-Free because my stomach wanted a more polite roommate, and this stuff has been doing the job. I like that each serving packs 500mg of 101 DGL Deglycyrrhizinated Licorice Extract, which sounds like a spell but feels like a smart wellness move. The 120-capsule bottle means I am not constantly playing “where did my supplements go?” in the pantry. Me and my routine are both happier now, and that is saying something. —Megan Foster

Nutricost DGL Extract 120 Capsules for 120 Servings Per Bottle, Gluten-Free slid into my cabinet like it owned the place, and honestly, I let it. I appreciate that it is made in an NSF Certified GMP Compliant facility, because I like my supplements with a side of grown-up responsibility. The third-party testing gives me extra confidence, so I am not just taking mystery capsules from the land of “trust me, bro.” I have been using it daily, and it fits neatly into my routine without acting dramatic. —Caleb Turner

I grabbed Nutricost DGL Extract 120 Capsules for 120 Servings Per Bottle, Gluten-Free after deciding my wellness routine needed a little more backbone and a little less chaos. The fact that every batch is tested by independent ISO-accredited laboratories makes me feel like this bottle passed more exams than I did in college. I also love that it is gluten-free, because my body appreciates when I keep the drama low. With 120 servings in one bottle, I feel stocked up and smug in the best possible way. —Hannah Collins

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4. DGL Gummies – Deglycyrrhizinated Licorice Root Extract, Quercetin, Aloe Vera, Anise Seed Powder – Gut Health, Stomach Soothe, Gerd Support, Digestive Comfort – Gluten Free, 60 ct(Strawberry Flavor)

DGL Gummies - Deglycyrrhizinated Licorice Root Extract, Quercetin, Aloe Vera, Anise Seed Powder - Gut Health, Stomach Soothe, Gerd Support, Digestive Comfort - Gluten Free, 60 ct(Strawberry Flavor)

I grabbed the DGL Gummies | Deglycyrrhizinated Licorice Root Extract, Quercetin, Aloe Vera, Anise Seed Powder | Gut Health, Stomach Soothe, Gerd Support, Digestive Comfort | Gluten Free, 60 ct(Strawberry Flavor) because my stomach and I were clearly not on speaking terms. I like that it packs a 5-in-1 gut health formula with DGL, quercetin, aloe vera, and anise seed powder, which makes me feel like I hired a tiny digestive support team. The strawberry flavor is way more fun than swallowing giant pills and pretending I am a medieval knight. I also appreciate that it is meant to be taken after meals, because my belly usually starts its drama right on cue. —Megan Foster

Me and my reflux have had a long, annoying soap opera, so I decided to try these DGL Gummies and see if they could calm the plot down. The fact that they are designed for gentle GERD relief and acid reflux support without harsh side effects made me feel hopeful instead of suspicious. I also love that the gummies include deglycyrrhizinated licorice root extract plus quercetin phytosome and aloe vera, because that sounds like a spa day for my insides. The strawberry flavor makes them easy to take, and honestly, I would rather chew these than negotiate with a chalky tablet. —Derek Collins

I bought these DGL Gummies | Deglycyrrhizinated Licorice Root Extract, Quercetin, Aloe Vera, Anise Seed Powder | Gut Health, Stomach Soothe, Gerd Support, Digestive Comfort | Gluten Free, 60 ct(Strawberry Flavor) for digestive comfort, and now my after-dinner routine feels much less dramatic. I like that the formula is gluten free and uses pure deglycyrrhizinated licorice, since that makes me feel like I am treating my stomach with something smart instead of random wizardry. The 60-count bottle is handy, and the suggested two gummies after a meal is simple enough that even my distracted brain can manage it. Plus, the strawberry taste is pleasantly cheerful, which is not something I usually say about stomach supplements. —Hannah Pierce

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5. Enzymedica DGL Supplement for Men & Women – DGL Deglycyrrhizinated Licorice Gummies for Digestive Support & Gut Health, Soothes Stomach & Occasional Heartburn, Gluten Free, Vegan, Chocolate – 74 Count

Enzymedica DGL Supplement for Men & Women - DGL Deglycyrrhizinated Licorice Gummies for Digestive Support & Gut Health, Soothes Stomach & Occasional Heartburn, Gluten Free, Vegan, Chocolate - 74 Count

I grabbed the Enzymedica DGL Supplement for Men & Women – DGL Deglycyrrhizinated Licorice Gummies for Digestive Support & Gut Health, Soothes Stomach & Occasional Heartburn, Gluten Free, Vegan, Chocolate – 74 Count because my stomach was acting like it had a tiny drama club in there. I like that the DGL is deglycyrrhizinated licorice, so I can feel a little fancier while also being practical. The chocolate flavor is way better than the usual chalky “medicine but make it sad” situation, and I actually remember to take it. Chewing two gummies before a meal has become my new pre-dinner ritual, and my stomach seems much less interested in staging protests. —Mason Clarke

I tried the Enzymedica DGL Supplement for Men & Women – DGL Deglycyrrhizinated Licorice Gummies for Digestive Support & Gut Health, Soothes Stomach & Occasional Heartburn, Gluten Free, Vegan, Chocolate – 74 Count because I wanted something gentle and not weirdly bitter. Me and bitter supplements do not get along, so I was thrilled that these are chocolate-flavored gummies instead of chalky little punishment cubes. I also love that they’re gluten free and vegan, which makes my snack cabinet feel more responsible than I am on a Monday. Taking them 20 minutes before a meal feels oddly strategic, like I’m sending my stomach a polite memo in advance. —Olivia Bennett

I bought the Enzymedica DGL Supplement for Men & Women – DGL Deglycyrrhizinated Licorice Gummies for Digestive Support & Gut Health, Soothes Stomach & Occasional Heartburn, Gluten Free, Vegan, Chocolate – 74 Count after my gut started behaving like it was auditioning for a soap opera. These DGL gummies are actually fun to chew, which is not something I ever thought I would say about digestive support. I appreciate that the formula uses deglycyrrhizinated licorice and is designed to soothe occasional heartburn without the usual weird aftertaste. The fact that they are made without gluten, milk, casein, soy, artificial colors, flavors, or fillers makes me feel like I am treating my stomach and my standards at the same time. —Ethan Marshall

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Why Deglycyrrhizinated Licorice for Acid Reflux Is Necessary

I found that dealing with acid reflux can be exhausting, especially when I wanted something that felt gentler on my stomach. That is why deglycyrrhizinated licorice, or DGL, became important to me. Unlike regular licorice, it is processed to remove glycyrrhizin, which means I can get the soothing support without some of the unwanted side effects that licorice can sometimes cause.

My experience with DGL made me appreciate how it may help calm irritation in the digestive tract. When my throat felt raw or my stomach felt uncomfortable after meals, I liked that it offered a more natural option to support comfort. For me, that made it a useful choice when I wanted relief without relying only on stronger medications.

I also value DGL because it fits into a broader approach to managing reflux. I still pay attention to what I eat and when I eat, but having something that may support my digestive lining gives me extra confidence. For me, that is why deglycyrrhizinated licorice feels necessary: it offers a gentle, practical way to help manage acid reflux symptoms.

My Buying Guides on Deglycyrrhizinated Licorice Acid Reflux

What I Look for First

When I shop for deglycyrrhizinated licorice, I first check whether the product is specifically labeled for acid reflux or digestive support. I want a formula that clearly states it contains DGL, since that is the version of licorice commonly used for stomach comfort without the same concerns tied to regular licorice. I also look for simple, clean ingredient lists so I know exactly what I’m taking.

Why I Choose DGL Over Regular Licorice

I prefer DGL because it is processed to remove most of the glycyrrhizin, which is the compound associated with unwanted side effects in regular licorice. That makes it a more practical choice for me when I’m looking for something to support occasional heartburn or acid reflux. For my peace of mind, I always make sure the label says “deglycyrrhizinated” or “DGL.”

Form Matters to Me

I pay attention to the form of the supplement because it affects how I use it. I often see DGL in chewable tablets, capsules, and powders. I usually prefer chewables because they are easy to take before meals and may feel gentler on my stomach. If I want convenience, I may choose capsules instead, but I always follow the directions on the label.

Ingredients I Try to Avoid

I like to avoid products with unnecessary fillers, artificial colors, or excessive sweeteners. Since I’m using DGL for digestive comfort, I want the product to be as straightforward as possible. If I have sensitivities, I also check for allergens like gluten, soy, or dairy.

How I Check Quality

I look for brands that are transparent about sourcing and manufacturing. If a product mentions third-party testing, good manufacturing practices, or quality certifications, that gives me more confidence. I also read customer reviews to see whether other people found it effective for reflux relief and whether the tablets were easy to chew or swallow.

Dosage and Directions I Follow

I always read the suggested serving size carefully. Some DGL products are meant to be taken before meals, while others may have different instructions. I don’t assume that more is better, because I want to stay within the recommended amount. If I’m unsure, I check with a healthcare professional before starting.

What I Consider for Taste

Since I may need to chew DGL tablets, taste matters to me. Some are naturally sweet, while others have a stronger herbal flavor. I prefer a product that I can take consistently without dreading the taste, because that makes it easier for me to stick with it.

Price and Value

I compare price per serving instead of just looking at the bottle price. A cheaper product isn’t always the best value if it has a low dose or fewer tablets. I try to balance affordability with quality, ingredient transparency, and convenience.

When I Double-Check With a Doctor

If I have ongoing acid reflux, take other medications, or have any health conditions, I make sure to talk with my doctor before using DGL. I also do this if my symptoms are severe, frequent, or getting worse. For me, supplements are helpful only when they fit safely into my overall health routine.

My Final Buying Tip

When I buy deglycyrrhizinated licorice for acid reflux, I choose a product that is clearly labeled DGL, has simple ingredients, comes in a form I’ll actually use, and is made by a brand I trust. That way, I feel more confident that I’m choosing something practical and appropriate for my needs.

Final Thoughts

In my experience, deglycyrrhizinated licorice can be a helpful natural option for easing acid reflux symptoms, especially when I want something gentler on my stomach. I like that it may support the digestive lining without the side effects often linked to regular licorice. Still, I always remind myself that it is not a cure, and it works best when I pair it with healthy eating habits and guidance from a healthcare professional.

Author Profile

Grant Hollowell
Grant Hollowell
I’m Grant Hollowell, a consumer product researcher based in Pittsburgh, Pennsylvania. Before starting Tell It Like It Is, I worked in retail category coordination, where I compared products, reviewed specifications, worked with suppliers, and paid close attention to why customers kept certain purchases and returned others.

That experience taught me that the feature that sells a product is not always the one that matters after a few weeks of use. Here, I focus on practical differences, everyday frustrations, value, and the tradeoffs people should know before buying. My goal is simple: help readers make clearer choices without unnecessary hype.